产品编号：C178540

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	C178540
名称:	(αR,γS)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic acid α-ethyl Ester
别名:	Sacubitril methyl ester; 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-methoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoic acid
分子式:	C₂₃H₂₇NO₅
分子量:	397.46
类别:	Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(αR,γS)-γ-[(3-Carboxy-1-oxopropyl)amino]-α-methyl-[1,1'-biphenyl]-4-pentanoic acid α-ethyl Ester is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
参考文献	McMurray, J., et al.: N. Eng. J. Med., 371 (2014);