产品编号：C175608

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	C175608
名称:	Candesartan N-Trityl O-Tri-acetyl Acyl-glucuronide Methyl Ester
别名:	(2S,3R,4S,5S,6S)-2-((2-Ethoxy-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-benzo[d]imidazole-7-carbonyl)oxy)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
分子式:	C₅₆H₅₀N₆O₁₂
外观:	白色固体
分子量:	999.03
溶解度:	Acetone, Dichloromethane, Ethyl Acetate, Methanol, Toluene
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Candesartan N-Trityl O-Tri-acetyl Acyl-glucuronide Methyl Ester is an intermediate in synthesizing Candesartan Acyl-Glucuronide (C175605), a metabolite of Candesartan (C175575), an angiotensin II type-1 receptor antagonist. Used in treatment of congestive heart failure. Antihypertensive.
参考文献	Kaur, N., et al.: Bioorg. Med. Chem., 16, 10210 (2008); Funao, K., et al.: Mol. Med. Rep., 2, 193 (2009); Yoshikawa, M., et al.: J. Cardiovas. Pharmacol., 53, 179 (2009); Palaniyappan, A., et al.: Mol. Cell. Biochem., 321, 9 (2009)