产品编号：B810545

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	B810545
名称:	BX 471
别名:	(2R)-1-[[2-[(Aminocarbonyl)amino]-4-chlorophenoxy]acetyl]-4-[(4-fluorophenyl)methyl]-2-methylpiperazine; (2R)-1-[[[4-Chloro-2-(ureido)phenoxy]methyl]carbonyl]-2-methyl-4-(4-fluorobenzyl)piperazine; N-[5-Chloro-2-[2-[(2R)-4-[(4-fluorophenyl)methyl]-2-methyl-1-piperazinyl]-2-oxoethoxy]phenyl]urea
CAS号:	217645-70-0
分子式:	C₂₁H₂₄ClFN₄O₃
分子量:	434.89
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	BX 471 iS A C-C chemokine receptor 1(CCR1) antagonist. The CCR1 is implicated in diseases such as multiple myeloma, rheumatoid arthritis, and multiple sclerosis and therefore BX 471 may be used in treatment of such diseases.
参考文献	Meritt, J., et al.: J. Med. Chem., 52, 1295 (2009); Choi, S., et al.: Chemokine-inhibiting piperazine derivatives and their use to treat multiple myeloma, WO Patent 2005077372, Aug 25, 2005;