产品编号：B809085

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B809085
名称:	tert-​Butyl 6-​Cyano-​2-​(2-​(4-​ethyl-​3-​iodophenyl)​propan-​2-​yl)​benzofuran-​3-​carboxylate
别名:	6-​Cyano-​2-​[1-​(4-​ethyl-​3-​iodophenyl)​-​1-​methylethyl]​-​3-bBenzofurancarboxylic Acid 1,​1-​Dimethylethyl Ester
CAS号:	1256585-29-1
分子式:	C₂₅H₂₆INO₃
分子量:	515.38
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	tert-​Butyl 6-​Cyano-​2-​(2-​(4-​ethyl-​3-​iodophenyl)​propan-​2-​yl)​benzofuran-​3-​carboxylate is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
参考文献	Kinoshita, K. et al.: J. Med. Chem., 64, 6286 (2011); Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);