产品编号：B796595

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	B796595
名称:	tert-Butyl (3-(4-Methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamido)-5-(trifluoromethyl)phenyl)carbamate
分子式:	C₂₉H₂₇F₃N₆O₃
外观:	Beige Solid
分子量:	564.56
储存:	Room Temperature
溶解度:	Dichloromethane; Methanol
类别:	Building Blocks; Miscellaneous;
应用:	tert-Butyl (3-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzamido)-5-(trifluoromethyl)phenyl)carbamate is an intermediate for the synthesis of Nilotinib 3-Imidazolyl N-oxide (M326296), which is an impurity compound of Nilotinib (N465300), useful in the treatment of chronic myelogenous leukemia.
参考文献	Wei-Sheng H., et al.: Synthesis, 14, 2121 (2007); Corbin, A., et al.: J. Biol. Chem., 277, 32214(2002), Golemovic, M., et al.: Clin. Cancer Res., 11, 4941 (2005), Gleixner, K., et al.: Blood, 107, 752 (2006), Nicolini, F., et al.: Leukemia, 20, 1061 (2006),