产品编号：B710035

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	B710035
名称:	Butyl 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ester
别名:	Butyl 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate;
CAS号:	1619982-02-3
分子式:	C₂₀H₂₄N₂O₃S
外观:	Off-Wite Solid
熔点:	115-117°C
分子量:	372.48
储存:	冰箱保存
溶解度:	DMSO (Slightly), Methanol (Slightly)
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	Butyl 2-[3-Cyano-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazolecarboxylic Acid Ester is derived from Febuxostat (F229000), which is a xanthine oxidase/xanthine dehydrogenase inhibitor and used for treatment of hyperuricemia and chronic gout. 40-120 mg/day febuxostat was proven effective in lowering serum urate levels when administered to manage hyperuricemia in patients with gout.
参考文献	Osada, Y., et al.: Eur. J. Pharmacol., 241, 183 (1993), Okamoto, K., et al.: J. Biol. Chem., 278, 1848 (2003), Mayer, M.D., et al.: Am. J. Therap., 12, 22 (2005), Tomlinson, B., et al.: Curr. Opin. Invest. Drugs, 6, 1168 (2005)