产品编号：B694460

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	B694460
名称:	tert-​Butyl 4-​(4-​Ethyl-​3-​iodophenyl)​-​4-​methyl-​3-​oxopentanoate
别名:	4-​Ethyl-​3-​iodo-​γ,​γ-​dimethyl-​β-​oxo-benzenebutanoic Acid 1,​1-​Dimethylethyl Ester;
CAS号:	1256584-74-3
分子式:	C₁₈H₂₅IO₃
分子量:	416.29
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	tert-​Butyl 4-​(4-​Ethyl-​3-​iodophenyl)​-​4-​methyl-​3-​oxopentanoate is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
参考文献	Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);