产品编号：B683485

产品规格：2.5g

产品价格：面议

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产品详情

标准品编号:	B683485
名称:	8-Bromo-3,9-dihydro-3-methyl-1H-purine-2,6-dione
别名:	3-Methyl-8-bromoxanthine; 8-Bromo-3-methyl-3,7-dihydropurine-2,6-dione; 8-Bromo-3-methylxanthine; Linagliptin 8-Bromo Impurity
CAS号:	93703-24-3
分子式:	C₆H₅BrN₄O₂
分子量:	245.03
类别:	Building Blocks; Miscellaneous;
应用:	8-Bromo-3,9-dihydro-3-methyl-1H-purine-2,6-dione, is a substituted derivative of Xanthine (X499950), found in animal organs, yeast, potatoes, coffee beans, tea. It can also be used for the synthesis of Linagliptin (L465900), which is a novel potent and selective dipeptidyl peptidase-4 (DPP-4) inhibitor with potential use in the treatment of type 2 diabetes.
参考文献	Mueller, C. et. al: Handbook Exp. Pharmacol. 200,151(2011); Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011); Mtthias E., et. al: J. Med. Chem., 50, 6450 (2007);