产品编号：B676633

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	B676633
名称:	(+/-)-trans-anti-N2-BPDE-dG-15N5
别名:	[7S-(7α,8β,9β,10α)]-2'-Deoxy-N-(7,8,9,10-tetrahydro-7,8,9-trihydroxybenzo[a]pyren-10-yl)guanosine-15N5; Benzo[a]pyrene, guanosine deriv.-15N5; (+/-)-trans-anti-7,8,9-Trihydroxy-10-(2'-deoxyguanosin-2-yl)benzo[a]pyrene-15N5
参考CAS:	未标记：85026-87-5
分子式:	C₃₀H₂₉¹⁵N₅O₇
分子量:	576.55
类别:	Standards; Isotopic Labeled Analogues; Environmental Standards, Mutagens and Metabolites;
应用:	(+/-)-trans-anti-N2-BPDE-dG-15N5 is an isotope labelled analog of (-)-trans-anti-N2-BPDE-dG (B676630), which is used in the study of carcinogen-DNA adducts and their role in affecting eukaryotic DNA methyltransferases. Cluster-type DNA damage is often seen in DNA and is usually skipped by base excision repair.
参考文献	Skosareva, L. et al.: DNA Repair., 11, 367 (2012); Minero, A. et al.: FEBS J. et al.: 279, 3965 (2012); Hoare, S. et al.: Biochem., 39, 12252 (2000); Subach, O. et al.: Biochem., 45, 6142 (2006);