产品编号:B602753
产品规格:50mg
产品价格:面议
| 标准品编号: | B602753 |
| 名称: | N-Boc Acetaminophen-cysteine |
| 别名: | (R)-3-((4-Acetamidophenyl)thio)-2-((tert-butoxycarbonyl)amino)propanoic Acid |
| 分子式: | C₁₆H₂₂N₂O₅S |
| 外观: | 白色固体 |
| 分子量: | 354.42 |
| 溶解度: | Methanol |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | N-Boc Acetaminophen-cysteine is an intermediate in the synthesis of Acetaminophen-cysteine (A161255). Acetaminophen-cysteine is a metabolite of Acetaminophen (A161220) and a serum biomarker of acetaminophen exposure (1,2). Acetaminophen-cysteine can be used to identify acetaminophen-induced acute liver failure when standard testing is inconclusive. Acetaminophen is oxidized by cytochrome P450 to a reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI), which can react with cysteine residues of hepatic proteins to yield Acetaminophen-cysteine (3). |
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