产品编号：B595839
产品规格：2.5mg
产品价格：面议
| 标准品编号: | B595839 |
| 名称: | (Rac)-BL 918 |
| 别名: | α-[[[[3,5-Bis(trifluoromethyl)phenyl]amino]thioxomethyl]amino]-N-(2,4-difluorophenyl)-benzeneacetamide |
| 分子式: | C₂₃H₁₅F₈N₃OS |
| 外观: | 白色至白色固体 |
| 熔点: | 157-160°C |
| 分子量: | 533.44 |
| 储存: | -20°C Freezer |
| 溶解度: | DMSO (Slightly), Methanol (Slightly) |
| 类别: | Standards; Molecular Biology; Enzyme Activators and Inhibitors; |
| 应用: | (Rac)-BL 918 is the racemate of BL 918 (B595838), a potent small-molecule activator of UNC-51-like kinase 1 (ULK1), a serine-threonine kinase involved in autophagy. Promotes cytoprotective autophagy in MPP+-treated SH-SY5Y cells, via the ULK complex. Improves motor dysfunction and reduces loss of dopaminergic neurons, mediated by MPTP, in in vivo models of Parkinson’s disease. |
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