产品编号：B411990

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	B411990
名称:	BGP 15
别名:	N-[2-Hydroxy-3-(1-piperidinyl)propoxy]-3-pyridinecarboximidamide Dihydrochloride;
CAS号:	66611-37-8
备用CAS:	Free Form: 66611-38-9
分子式:	C₁₄H₂₂N₄O₂ • 2(HC l)
分子量:	278.357292
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	BGP 15 is a calcipotriene-based vitamin D3 analog that inhibits poly(ADP-ribose) polymerasesis (PARP), a class of enzymes that regulate DNA repair and apoptosis (1). BGP 15 is also a cardioprotective agent (2). Also, BPG 15 improves mitochondrial function, protects neurons from dying in vitro and in vivo, and promotes cardiac innervation in vivo.
文献	Sarszegi, Z., et al.: Mol. Cell. Biol., 365, 129-137 (2012); Ohlen, S. B., et al.: Proc. Natl. Acad. Sci. U.S.A., 114, 5035-5040 (2017)