产品编号：B397965

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	B397965
名称:	4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-4-methyl-5-oxo-5-propoxypentan-2-yl)amino)-4-oxobutanoic acid
分子式:	C₂₅H₃₁NO₅
分子量:	425.52
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-4-methyl-5-oxo-5-propoxypentan-2-yl)amino)-4-oxobutanoic acid is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan. The combination drug, valsartan/sacubitril, known during trials as LCZ696 and marketed under the brand name, Entresto, is a treatment for heart failure.
文献	McMurray, J., et al.: N. Eng. J. Med., 371 (2014);