产品编号：B119183

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	B119183
名称:	BCECF/AM
别名:	3',6'-Bis(acetyloxy)-5(or 6)-[[(acetyloxy)methoxy]carbonyl]-3-oxo-bis[(acetyloxy)methyl] Ester Spiro[isobenzofuran-1(3H),9'-[9H]xanthene]-2',7'-dipropanoic Acid
CAS号:	117464-70-7
分子式:	C₁₀₉H₉₈O₄₄
分子量:	2111.92
类别:	Research Tools; Materials; Dyes;
应用:	BCECF/AM, a membrane-permeable fluorescent indicator for the measurement of cytoplasmic pH with an Abs/Em = 503/520 nm. The compound is an acetoxymethyl ester of BCECF, is a variable mixture of cell-permeable ester derivatives of BCECF that are hydrolyzed by cytosolic esterases to yield intracellularly trapped indicator BCECF. BCECF/AM is a selective vacuolar accumulation of the fluorescent pH-indicator used to monitor intracellular pH changes in mammalian fibroblasts, gastric cells, lymphocytes, myocytes, and distal convoluted tubules.
文献	1. Weiner, I.D., et al. 1989. Am. J. Physiol. 256: F957-F964. PMID: 27191252. Miyata, H., et al. 1989. Biochem. Biophys. Res. Commun. 163: 500-505. PMID: 27752823. Hayashi, H., et al. 1992. Am. J. Physiol. 262: C628-C634. PMID: 15502074. Sasaki, S., et al. 1992. Biochim. Biophys. Acta. 1137: 45-51. PMID: 13271525. Futsaether, C.M., et al. 1993. Can. J. Microbiol. 39: 180-186. PMID: 8467419