产品编号：A884803
产品规格：5mg
产品价格：面议
| 标准品编号: | A884803 |
| 名称: | 7-Azido-4-methylcoumarin |
| 别名: | 7-Azido-4-methyl-2H-1-benzopyran-2-one 4-Methyl-7-azidocoumarin |
| CAS号: | 95633-27-5 |
| 分子式: | C₁₀H₇N₃O₂ |
| 分子量: | 201.18 |
| 类别: | Research Tools; |
| 应用: | 7-Azido-4-methylcoumarin is a highly sensitive and selective fluorogenic H2S probe. 7-Azido-4-methylcoumarin is a tool for monitoring the activity of pyridoxal-5'-phosphate (PLP)-dependent enzymes (e.g. cystathionine β-synthase (CBS), cystathionine γ-lyase (CGL) and tryptophan synthase (TS)) and to identify novel cystathionine β-synthase (CBS) inhibitors and activators. The aromatic azide moiety is selectively reduced in the presence of H2S, producing the fluorescent 7-amino-4-methylcoumarin (AMC) with a concomitant increase in fluorescence with ?ex = 365 nm and ?em = 450 nm. It has been characterized as a novel fluorescent photoactive probe for use in photoaffinity labeling of the substrate binding site of human phenol sulfotransferase (SULT1A1 or P-PST-1) |
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