产品编号：A794715

产品规格：50mg

产品价格：面议

---

产品详情

标准品编号:	A794715
名称:	AVL-292
别名:	CC 292; N-[3-[5-Fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]pyrimidin-4-ylamino]phenyl]acrylAmide; Spebrutinib; N-[3-[[5-Fluoro-2-[[4-(2-methoxyethoxy)phenyl]amino]-4-pyrimidinyl]amino]phenyl]-2-propenamide
CAS号:	1202757-89-8
分子式:	C₂₂H₂₂FN₅O₃
分子量:	423.44
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	AVL-292 is a potent and specific Bruton's tyrosine kinase (Btk) inhibitor. Studies showed that AVL-292 used in combination with Carfilzomib (C183460) impacted the bone microenvironment in a multiple myeloma model with resultant antimyeloma activity.
文献	Eda, H., et al.: Leukemia, 28, 1892 (2014); Evans, E.K., et al.: J. Pharmacol. Exp. Ther., 346, 219 (2013)