产品编号：A787035

产品规格：0.5mg

产品价格：面议

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产品详情

标准品编号:	A787035
名称:	(-)-Ascofuranone
别名:	3-Chloro-4,6-dihydroxy-2-methyl-5-[(2E,6E)-3-methyl-7-[(2S)-tetrahydro-5,5-dimethyl-4-oxo-2-furanyl]-2,6-octadien-1-yl]benzaldehyde;[S-(E,E)]-3-Chloro-4,6-dihydroxy-2-methyl-5-[3-methyl-7-(tetrahydro-5,5-dimethyl-4-oxo-2-furanyl)-2,6-octadienyl]-benzaldehyde; Ascofuranone;
CAS号:	38462-04-3
分子式:	C₂₃H₂₉ClO₅
分子量:	420.93
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Antibotics;
应用:	(-)-Ascofuranone is an antibiotic with antitumor activity. It suppresses PMVIP(LA)mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanisms. (-)-Ascofuranone was effective in the treatment against Trypanosoma brucei brucei infection in mice.
文献	Yabu, Y., et al.: Parasitol. Int., 52, 155 (2003); Cho, H., et al.: Carcinogenesis, 28, 1104 (2007);