产品编号：A661585

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A661585
名称:	(2R,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetic Acid Salt
分子式:	C₁₁H₂₁NO₄ · C₂HF₃O₂
外观:	Colorless Oil
分子量:	231.2911402
储存:	-20°C Freezer
溶解度:	Chloroform; Ethyl Acetate; Methanol; Acetone; Acetonitrile
类别:	Building Blocks; Chiral Molecules;
应用:	(2R,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetic Acid Salt is an intermediate for the synthesis of Carfilzomib (2R,4S)-Diol (C183470), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.
文献	Fostier, K., et al.: Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al.: J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al.: Drugs., 72, 2023 (2012);