产品编号：A635158

产品规格：2.5mg

产品价格：面议

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产品详情

标准品编号:	A635158
名称:	(2R,3R,E)-2-Amino-3-hydroxyoctadec-4-en-1-yl dimethyl Phosphate-13C2,D2
分子式:	C₂₃¹³C₂H₄₈D₂NO₇P
外观:	Light Brown Oil
分子量:	511.64
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	(2R,3R,E)-2-Amino-3-hydroxyoctadec-4-en-1-yl dimethyl Phosphate-13C2,D2 iis an intermediate in the synthesis of D-erythro-Sphingosine-1-phosphate-13C2,D2 (S681502), which is a labelled putative lipid second messenger; found to inhibit cellular mobility of melanoma cells at very low concentrations with no toxic effects thereby making it a possible agent for prevention of tumor cell metastasis and inflammatory processes; mobilizes intracellular calcium stores; decreases cellular cAMP; activates phospholipase D; does not inhibitprotein kinase C.
文献	Zhang, H., et al.: J. Cell Biol., 114, 155 (1991) Sadahira, Y., et al.: Proc. Natl. Acad. Sci. USA (1992), Cuvillier, O., et al.: Nature, 381, 800 (1996)