产品编号：A622635

产品规格：25mg

产品价格：面议

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产品详情

标准品编号:	A622635
名称:	2-(4-Aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid Methyl Ester Dihydrochloride
别名:	2-(4-Aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxyphenyl)-3-isoquinolinecarboxylic Acid Methyl Ester Hydrochloride (1:2); T1032
CAS号:	212498-37-8
备用CAS:	Free Base: 212500-02-2
分子式:	C₃₂H₃₁Cl₂N₃O₇
分子量:	640.51
类别:	Standards; Enzyme Activators and Inhibitors;
应用:	2-(4-Aminophenyl)-1,2-dihydro-1-oxo-7-(2-pyridinylmethoxy)-4-(3,4,5-trimethoxypheny Tl)-3-isoquinolinecarboxylic Acid Dihydrochloride, is a selective substrate for cytochrome P450 3A5 (CYP3A5). These compounds are also 4-Aryl-1-isoquinolinone Derivatives, which are shown to be novel, potent, and selective Phosphodiesterase 5 (PDE5) Inhibitors.
参考:	Song, X., et al.: Bio. Med. Chem. Lett., 22, 1611(2012); Tatsuzo, U., et al.: J. Med. Chem., 44, 2204 (2001);