产品编号：A621703

产品规格：250mg

产品价格：面议

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产品详情

标准品编号:	A621703
名称:	3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-N-(3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)propanamide
分子式:	C₄₇H₄₆N₁₂O₃
状态：	Off-white Solid
分子量:	826.95
溶解性:	Dichloromethane, Methanol
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	3-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)-N-(3-(4-phenoxyphenyl)-1-(piperidin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)propanamide is an intermediate in the synthesis of Namino-{3-[(R)-1-(3-(4-Amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl]-propionyl} Ibrutinib (A619015), which is an impurity of Ibrutinib (I124970), a highly selective Bruton’s tyrosine kinase (Btk) irreversible inhibitor.
参考:	MacGlashan, D., et. al.: Int. Immunol., 11, 475 (2011)