产品编号：A614410

产品规格：5mg

产品价格：面议

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产品详情

标准品编号:	A614410
名称:	AMG 837
别名:	(βS)-β-1-Propynyl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]-benzenepropanoic Acid; (βS)-β-1-Propyn-1-yl-4-[[4'-(trifluoromethyl)[1,1'-biphenyl]-3-yl]methoxy]benzenepropanoic Acid;
CAS号:	865231-46-5
分子式:	C₂₆H₂₁F₃O₃
分子量:	438.44
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	AMG 837 is a potent GPR40 agonist. GPR40 is a polyunsaturated fatty acid receptor that is involved with many systemic effects, which are beneficial for metabolic and inflammatory diseases. GPR40 has also been implicated as a target for treating obesity.
参考:	Dragano, N. R. V., et al.: J Neuroinflammation. 14, 91 (2017); Houze, J. B., et al.: Bioorg Med Chem Lett. 22, 1267 (2012)