产品编号：A603388

产品规格：5mg

产品价格：面议

---

产品详情

标准品编号:	A603388
名称:	5-Amino-2-chlorobenzotrifluoride N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester
别名:	(2R,3R,4S,5S,6S)-2-((4-Chloro-3-(trifluoromethyl)phenyl)amino)-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl Triacetate
分子式:	C₂₀H₂₁ClF₃NO₉
状态：	Brown Solid
分子量:	511.83
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
应用:	5-Amino-2-chlorobenzotrifluoride N-Dehydroxy-2,3,4-tri-O-acetyl-D-glucuronic Acid Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt (R143320), which is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
参考:	Leuner, C., et al.: Eur. J. Pharm. Biopharm., 50, 47 (2000)