产品编号：A179045

产品规格：5g

产品价格：面议

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产品详情

标准品编号:	A179045
名称:	1-Acetyl-4-(4-hydroxyphenyl)piperazine
别名:	1-[4-(4-Hydroxyphenyl)-1-piperazinyl]ethanone; 4-(4-Acetylpiperazino)phenol; 1-Acetyl-4-(p-hydroxyphenyl)piperazine; Ketoconazole Intermediate (branched chain of ketoconazole)
CAS号:	67914-60-7
分子式:	C₁₂H₁₆N₂O₂
状态：	白色至白色固体
熔点：	180-182ºC
分子量:	220.27
储存：	-20°C Freezer
溶解性:	DMSO (Slightly), Methanol (Slightly)
类别:	Building Blocks; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-Acetyl-4-(4-hydroxyphenyl)piperazine is an intermediate used to prepare Ketoconazole (K186000) which inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo.
参考:	Lambert, A., et al.: Biochem. Pharmacol., 35, 3999 (1986), Van Wauwe, J.P. and Janssen, P.A.J., J. Med. Chem., 32, 2231 (1989), Nardone, P.A., et al.: . Surg. Res., 44, 425 (1988), Tucker, W.F.G., et al.: Br. Med. J., 293, 882 (1986)

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