产品编号：A160815

产品规格：100mg

产品价格：面议

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产品详情

标准品编号:	A160815
名称:	1-​[4-​[[(3R,​4R)​-​1-​Acetyl-​4-​methyl-​3-​piperidinyl]​methylamino]​-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​7-​yl]​ehtanone
CAS号:	1608117-47-0
分子式:	C₁₇H₂₃N₅O₂
分子量:	329.4
类别:	Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	1-​[4-​[[(3R,​4R)​-​1-​Acetyl-​4-​methyl-​3-​piperidinyl]​methylamino]​-​7H-​pyrrolo[2,​3-​d]​pyrimidin-​7-​yl]​ehtanone is an intermediate in the synthesis of Tofacitinib Impurity Z (T528030), which is an impurity of Tofacitinib (T528000), an enantiopure stereoisomer of the drug, Janus kinase 3 (Jak3) inhibitor (CP-690,550) that has been found to inhibit selected members of the STE7 and STE20 subfamily of kinases.
参考:	Jiang, J., et. al.: J. med. Chem., 51, 8012 (2008)