产品编号:A115605
产品规格:5mg
产品价格:面议
| 标准品编号: | A115605 |
| 名称: | Acalabrutinib |
| 别名: | 4-[8-amino-3-[(2S)-1-(1-oxo-2-butyn-1-yl)-2-pyrrolidinyl]imidazo[1,5-a]pyrazin-1-yl]-N-2-pyridinylbenzamide; ACP 196 |
| CAS号: | 1420477-60-6 |
| 分子式: | C₂₆H₂₃N₇O₂ |
| 状态: | 淡黄色固体 |
| 熔点: | >133°C (dec.) |
| 分子量: | 465.51 |
| 储存: | 冰箱保存 |
| 溶解性: | DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) |
| 类别: | Standards; Pharmaceutical/API Drug Impurities/Metabolites; |
| 应用: | Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL). |
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