产品编号：A112500

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	A112500
名称:	ABT 263
别名:	4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide; Navitoclax
CAS号:	923564-51-6
分子式:	C₄₇H₅₅ClF₃N₅O₆S₃
状态：	Pale Yellow to Pale Brown Solid
熔点：	>122°C (dec.)
分子量:	974.61
储存：	-20°C Freezer, Under Inert Atmosphere
溶解性:	Chloroform, DMSO, Methanol
类别:	Standards; Chiral Molecules; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate. Potent Bcl-2 family inhibitor.
参考:	Adams, J., et al.: Science, 281, 1322 (1998), Degterev, A., et al.: Nat. Cell. Biol., 3, 173 (2001), Kitada, S., et al.: J. Med. Chem., 46, 4259 (2003), Danial, N., et al.: Clin. Cancer Res., 13, 7254 (2007),

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