产品编号：A101010

产品规格：10mg

产品价格：面议

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产品详情

标准品编号:	A101010
名称:	A350619 Hydrochloride
别名:	3-[2-[(4-Chlorophenyl)thio]phenyl]-N-[4-(dimethylamino)butyl]-2-propenamide, , Hydrochloride;
CAS号:	1217201-17-6
备用CAS:	Free Base: 538368-27-3
分子式:	C₂₁H₂₆Cl₂N₂OS
分子量:	425.41
类别:	Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:	A350619 Hydrochloride is an activator of guanylyl cyclase (sGC). It activates basal sGC and synergistically activates sGC in the presence of NO. Acting as an sGC stimulator, it may be more effective than PDE5 inhibitors in the treatment of ED.
参考:	Gur, S. et al.: Curr. Pharm. Des., 16, 1619 (2010); Nandhakumar, J. et al.: J. Neurol. Neurophysiol., 2, 1000110 (2011); Miller, L. et al.: Life Sci., 72, 1015 (2003);