N-(2-Phenoxyphenyl)methanesulfonamide; Nimesulide EP Impurity B
CAS号:
51765-51-6
分子式:
C₁₃H₁₃NO₃S
外观:
白色至白色固体
熔点:
122-125°C
分子量:
263.31
储存:
-20°C Freezer
溶解度:
Chloroform (Slightly), DMSO
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
2'-Phenoxymethanesulfonanilide is a metabolite of nimesulide (N477500), which is an antiinflammatory agent. It preferentially inhibits COX-2 over COX-1 and suppresses chemical-induced carcinogenesis in mice and rats. Nimesulide also nhibits LPS-induced TNF-alpha production.
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