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产品编号:T295600
产品名称:(2R,4R)-rel-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid
产品CAS:80742-11-6
规格含量:250mg
产品价格:面议
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产品详细介绍
标准品编号:
T295600
名称:
(2R,4R)-rel-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester
别名:
cis-(±)-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic acid methyl ester;cis-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester
CAS号:
80742-11-6
分子式:
C₁₉H₁₈N₄O₆
外观:
Pale Yellow to Light Yellow Solid
熔点:
>164°C (dec.)
分子量:
398.37
储存:
Amber Vial, -20°C Freezer, Under inert atmosphere
溶解度:
DMSO (Slightly), Ethyl Acetate (Very Slightly, Heated), Methanol (Slightly)
稳定性:
Light Sensitive
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(2R,4R)-rel-1,2,3,4-Tetrahydro-6-methyl-2,4-bis(2-nitrophenyl)-5-pyrimidinecarboxylic Acid Methyl Ester is an impurity of Nifedipine (N457000); a dihydropyridine calcium channel blocker. Also used as an antihypertensive and antianginal.
参考文献
Karancsi, T., et al.: Acta Pharm. Hung., 66, 21 (1996); Poetter, H., et al.: J. Pharmaceut. Biomed., 6, 115 (1988); Ali, S.L., et al.: Anal. Profiles Drug Subs., 18, 221 (1989); Soons, P.A., et al.: J. Pharm. Biomed. Anal., 9, 475 (1991); Brown, M.J., et al.: Lancet, 356, 366 (2000)
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