对照品 > 对照品 > 自制对照品 >
产品基本信息
产品编号：M425462
产品名称：MM-419447-d4 Trifluoroacetic Acid Salt (Linaclotide Metabolite)
产品CAS：
规格含量：2.5mg
产品价格：面议
联系我们:
产品详细介绍
标准品编号:
M425462
名称:
MM-419447-d4 Trifluoroacetic Acid Salt (Linaclotide Metabolite)
别名:
L-cysteinyl-L-cysteinyl-L-α-glutamyl-L-tyrosyl-L-cysteinyl-L-cysteinyl-L-asparaginyl-L-prolyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteine-d4 Trifluoroacetic Acid Salt; 132: PN: US20050020811 SEQID: 125 Claimed Sequence-d4 Trifluoroacetic Acid Salt; 13: PN: WO2014151200 SEQID: 56 Claimed Protein-d4 Trifluoroacetic Acid Salt; 44: PN: US20120237593 SEQID: 56 Claimed Sequence-d4 Trifluoroacetic Acid Salt; 5: PN: WO2016015055 SEQID: 6 Claimed Sequence-d4 Trifluoroacetic Acid Salt; 652: PN: WO2007022531 PAGE: 248 Claimed Protein-d4 Trifluoroacetic Acid Salt; 65: PN: WO2005087797 SEQID: 71 Unclaimed Sequence-d4 Trifluoroacetic Acid Salt; 78: PN: US20090062207 SEQID: 81 Unclaimed Protein-d4; 80: PN: US20060281682 SEQID: 81 Claimed Protein-d4 Trifluoroacetic Acid Salt; 81: PN: US20060258593 S
参考CAS号:
Unlabelled: 832118-08-8
分子式:
C₅₀H₇₂D₄N₁₄O₁₉S₆ • x(C ₂HF₃O₂)
外观:
白色至白色固体
熔点:
>250°C (dec.)
分子量:
1373.64114
储存:
冰箱
溶解度:
Water (Slightly)
种类:
Research Tools; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
MM-419447-d4 Trifluoroacetic Acid Salt is a labelled analogue of MM-419447 (M425460), a Linaclotide metabolite, which is a guanylate cyclase-C agonist currently being studied in Phase 3 trials for the treatment of irritable bowel syndrome with constipation.
参考文献
Chey, W.D., et al.: Am. J. Gastroenterol., 107, 1702 (2012); Rao, S., et al.: Am. J. Gastroentrol., 107, 1714 (2012); Brierley, S.M., et al.: Curr. Opinion. Pharmacol., 12, 632 (2012);
您的位置：
