N-{2-Chloro-4-[(6,7-dimethoxyquinolin-4-yl)oxy]phenyl}-3-(5-methylisoxazol-3-yl)urea; AV 951; KRN 951; Kil 8951; N-[2-Chloro-4-[(6,7-dimethoxy-4-quinolyl)oxy]phenyl]-N'-(5-methyl-3-isoxazolyl)urea;
CAS号:
475108-18-0
分子式:
C₂₂H₁₉ ClN₄O₅
外观:
Pale Beige to Light Brown Solid
熔点:
>202°C (dec.)
分子量:
454.86
储存:
冰箱
溶解度:
DMSO (Slightly), Methanol (Slightly, Heated)
类别:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Tivozanib is known as an oral VEGF receptor tyrosine kinase inhibitor, exhibiting antitumor effects towards renal cell carcinoma.. Tivozanib suppresses angiogenesis by selectively inhibiting against vascular endothelial growth factor. Potent VEGFR inhibitor.
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