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SAR131675
产品基本信息
产品编号:S139510
产品名称:SAR131675
产品CAS:1092538-80-1
规格含量:25mg
产品价格:面议
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产品详细介绍
标准品编号: S139510
名称: SAR131675
别名: 2-Amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide; 2-Amino-1-ethyl-1,4-dihydro-7-(3-hydroxy-4-methoxy-3-methyl-1-butyn-1-yl)-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide
CAS号: 1092538-80-1
分子式: C₁₈H₂₂N₄O₄
外观: 白色至淡黄色固体
熔点: >206°C (dec.)
分子量: 358.39
储存: 冰箱
溶解度: Chloroform (Slightly), DMSO (Slightly)
类别: Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: SAR131675 is a potent and selective VEGFR-3 inhibitor. It inhibited VEGFR-3 tyrosine kinase activity and VEGFR-3 autophosphorylation in HEK cells. SAR131675 also dose dependently inhibited the proliferation of primary human lymphatic cells, induced by the VEGFR-3 ligands VEGFC and VEGFD.
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