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PF 431396
产品基本信息
产品编号:P218290
产品名称:PF 431396
产品CAS:717906-29-1
规格含量:10mg
产品价格:面议
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产品详细介绍
标准品编号: P218290
名称: PF 431396
别名: N-[2-[[[2-[(2,3-Dihydro-2-oxo-1H-indol-5-yl)amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]methyl]phenyl]-N-methylmethanesulfonamide; N-Methyl-N-[2-[[[2-[(2-oxo- 2,3-dihydro-1H-indol-5-yl)amino]-5-trifluoromethylpyrimidin-4-yl]amino]methyl]phenyl]methanesulfonamide; PF 431396;
CAS号: 717906-29-1
分子式: C₂₂H₂₁F₃N₆O₃S
外观: Gray Solid
熔点: >214°C (dec.)
分子量: 506.5
储存: -20°C Freezer
溶解度: DMSO (Slightly)
类别: Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: PF 431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively). Promotes osteoblast recruitment and activity, and stimulates bone formation in ovariectomized rats.
危险品: Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
参考文献


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