(E)-1-(2-hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; (2E)-1-(2-Hydroxy-4,6-dimethoxyphenyl)-3-(4-methoxyphenyl)-2-propen-1-one; 4-Methoxyflavokawain B; Flavokavin A
CAS号:
37951-13-6
分子式:
C₁₈H₁₈O₅
分子量:
314.33
种类:
Standards; Molecular Biology; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites; Natural Products;
应用:
Flavokawain A is achalcone found in the kava plant. It induces apoptosis in bladder cancer cells via a Bax protein-dependent and mitochondria-dependent apoptotic pathway. Furthermore, natural chalcones have beenimplicated as lead compounds for developing dual inhibitors againsthistone deacetylase enzymes (HDACs)and NF-κB.
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