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TAK-960-d3
产品基本信息
产品编号:T004942
产品名称:TAK-960-d3
产品CAS:
规格含量:10mg
产品价格:面议
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产品详细介绍
标准品编号: T004942
名称: TAK-960-d3
别名: 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide-d3;
参考CAS号: Unlabelled: 1137868-52-0
分子式: CH₃₁D₃F₃N₇O₃
分子量: 564.62
类别: Standards; Isotopic Labeled Analogues; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: Isotope labelled TAK-960 is a potent and selective inhibitor of polo-like kinase 1 (PLK1), a serine/threonine protein kinase involved in key processes during mitosis. TAK-960 has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 treatments has shown significant efficacy against multiple tumor xenografts and is a potential chemotherapeutic agent for patients with advanced tumors.
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