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PF-4708671
产品基本信息
产品编号:P294010
产品名称:PF-4708671
产品CAS:1255517-76-0
规格含量:10mg
产品价格:面议
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产品详细介绍
标准品编号: P294010
名称: PF-4708671
别名: 2-[[4-(5-ethyl-4-pyrimidinyl)-1-piperazinyl]methyl]-6-(trifluoromethyl)-1H-benzimidazole; PF 4708671;
CAS号: 1255517-76-0
分子式: C₁₉H₂₁F₃N₆
外观: Pale Purple Solid
熔点: >186°C (dec.)
分子量: 390.41
储存: -20˚C Freezer
溶解度: DMSO (Slightly, Sonicated), Methanol (Slightly)
类别: Research Tools; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用: PF-4708671 is a highly specific inhibitor of p70 ribosomal S6 kinase (S6K1). PF-4708671 inhibits S6K1-mediated phosphorylation of S6 protein in response to IGF-1 (insulin-like growth factor 1), while having no effect on highly related RSK (p90 ribosomal S6 kinase) and MSK (mitogen- and stress-activated kinase) kinases.
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