cis-4-​[[2-​(1H-​Benzimidazol-​6-​ylamino)​-​8-​quinazolinyl]​oxy]​-​cyclohexanol inhibits Traf2 and Nck-interacting protein kinase (TNIK). TNIK is involved with Canonical Wnt/b-catenin signalling, which has regulatory roles in maintaining intestinal stem cells and aberration in this pathway has been implicated in colorectal carcinogenesis. TNIK is a therapeutic target.
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