(R)-(-)-Methyl-2-hydroxy-2-methylbutanoate is derived from (S)-(-)-1-(1-Naphthyl)ethylamine (N368460), which is used in the asymmetric synthesis of α-cyanocarboxylates. Also used in the synthesis of chiral imadazolin-2-ylidene ligands used in organometallic catalysis. Chiral/Asymmetric synthesis.