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Regorafenib N-β-D-Glucuronide Methyl Ester
产品基本信息
产品编号:R143335
产品名称:Regorafenib N-β-D-Glucuronide Methyl Ester
产品CAS:
规格含量:1mg
产品价格:面议
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产品详细介绍
标准品编号: R143335
名称: Regorafenib N-β-D-Glucuronide Methyl Ester
别名: (2S,3S,4S,5R,6R)-Methyl 6-(1-(4-Chloro-3-(trifluoromethyl)phenyl)-3-(2-fluoro-4-((2-(methylcarbamoyl)pyridin-4-yl)oxy)phenyl)ureido)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate
分子式: C₂₈H₂₅ClF₄N₄O₉
外观: 白色固体
分子量: 672.97
类别: Standards; Pharmaceutical/API Drug Impurities/Metabolites; Carbohydrates and Oligosaccharides;
应用: Regorafenib N-β-D-Glucuronide Methyl Ester is an intermediate in the synthesis of Regorafenib N-β-D-Glucuronide Sodium Salt (R143320), which is a derivative of Regorafenib (R143000); a compound that inhibits PDGFR tyrosine kinase with IC50=83nM. Also useful for the treatment of inflammation and as an anti-proliferative agent.
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