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产品编号：H952495
产品名称：Boc-trans-Hydroxy-L-proline
产品CAS：13726-69-7
规格含量：5g
产品价格：面议
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产品详细介绍
标准品编号:
H952495
名称:
Boc-trans-Hydroxy-L-proline
别名:
(2S-trans)-4-Hydroxy-1,2-Pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) Ester; L-4-Hydroxy-1,2-pyrrolidinedicarboxylic Acid 1-tert-Butyl Ester; (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic Acid; (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic Acid; (2S,4R)-4-Hydroxy-1-(tert-butoxycarbonyl)pyrrolidine-2-carboxylic Acid; (2S,4R)-4-Hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic Acid; (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester; (4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline; 1-(tert-Butoxycarbonyl)-(2S,4R)-4-hydroxypyrrolidine-2-carboxylic Acid; Boc-L-trans-γ-hydroxyproline; Boc-trans-Hydroxy-L-proline; N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline; N-(tert-Butoxycarbonyl)hydroxy-L-proline; N-(tert-Bu
CAS号:
13726-69-7
分子式:
C₁₀H₁₇NO₅
外观:
白色固体
熔点:
120-124ºC
分子量:
231.25
储存:
-20°C Freezer, Under inert atmosphere
溶解度:
Chloroform (Sparingly), DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
种类:
Building Blocks; Chiral Molecules; Amino Acids;
应用:
boc-trans-Hydroxy-L-proline is used in the preparation of hydroxyproline derivatives. boc-trans-Hydroxy-L-proline is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.
参考文献
Nakanishi, K., et. al.: Peptide Sci., 47, 197 (2010); Singhvi, S.M., et al.: Br. J. Clin. Pharmacol., 25, 9 (1988); Sullivan, P.A., et al.: Am. J. Hypertension, 1, 280S (1988)
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