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产品编号：H456200
产品名称：Histidyl-Glycyl-Glutamyl-Glycyl-Threonyl-Phenylalanyl-Threonyl-Seryl-Aspartyl-Leucyl-Seryl
产品CAS：868249-02-9
规格含量：25mg
产品价格：面议
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产品详细介绍
标准品编号:
H456200
名称:
Histidyl-Glycyl-Glutamyl-Glycyl-Threonyl-Phenylalanyl-Threonyl-Seryl-Aspartyl-Leucyl-Seryl-Lysine xTFA Salt
别名:
His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys xTFA; HGEGTFTSDLSK xTFA; 29-(2-(2-Amino-3-(1H-imidazol-5-yl)propanamido)acetamido)-2-(4-aminobutyl)-20-benzyl-11-(carboxymethyl)-17,23-bis(1-hydroxyethyl)-5,14-bis(hydroxymethyl)-8-isobutyl-4,7,10,13,16,19,22,25,28-nonaoxo-3,6,9,12,15,18,21,24,27-nonaazadotriacontane-1,32-dioic Acid xTFA;
CAS号:
868249-02-9
分子式:
C₅₄H₈₃N₁₅O₂₁ • x( C₂HF₃O₂)
外观:
白色固体
熔点:
160-162ºC
分子量:
1278.32114
储存:
-20°C Freezer, Under inert atmosphere
溶解度:
Water (Slightly), Methanol (Very Slightly)
种类:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Histidyl-Glycyl-Glutamyl-Glycyl-Threonyl-Phenylalanyl-Threonyl-Seryl-Aspartyl-Leucyl-Seryl-Lysine xTFA is a metabolite from Exenatide trypsin (Exenatide Acetate, E957300) digestion. Exenatide acts as agonist of the glucagon-like peptide-1 (GLP-1) receptor.
参考文献
Pugazhenthi, U. et al.: Diabetol., 53, 2357 (2010); Li, C. et al.: Bioche,. Biophys. Res. Comm., 400, 563 (2010); Lupi, R. et al.: Diab. Obes. Metab., 10, 515 (2008); Kim, T.H. et al.: Bioconj. Chem., 22, 625 (2011);
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