4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic Acid; NSC 14972; Pyrofolic acid; p-[(2-Amino-4-hydroxy-6-pteridylmethyl)amino]benzoic Acid; Methotrexate EP Impurity D N-Desmethyl Impurity
杂质:
Methotrexate EP Impurity D N-Desmethyl Impurity
CAS号:
119-24-4
分子式:
C₁₄H₁₂N₆O₃
外观:
Light Yellow to Brown Solid
熔点:
>300°C (dec.)
分子量:
312.28
储存:
Hygroscopic, -20°C Freezer, Under inert atmosphere
溶解度:
Aqueous Base (Slightly), DMSO (Slightly)
类别:
Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
Pteroic Acid (Methotrexate EP Impurity D N-Desmethyl Impurity) is a constituent as well as a degradation product of Folic Acid (F680300) formed via enzymatic hydrolysis. has been shown to activate the glutamylation of methotrexate by folylpolyglutamate synthetase.
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