Nicotinic Acid Adenine Dinucleotide-d4 is the isotope labelled analog of Nicotinic Acid Adenine Dinucleotide (N429270); an analog of β-Nicotinamide Adenine Dinucleotide (N407775, Hydrate) which is a coenzyme consisting of an adenine base and a nicotinamide base connected by a pair of bridging phosphate groups. β-Nicotinamide Adenine Dinucleotide acts as a coenzyme in redox reactions, as a donor of ADP-ribose moieties in ADP-ribosylation reactions and also as a precursor of the second messenger molecule cyclic ADP-ribose. β-Nicotinamide Adenine Dinucleotide also acts as a substrate for bacterial DNA ligases and a group of enzymes called sirtuins that use NAD+ to remove acetyl groups from proteins.
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