(1S,2R)-Tranylcypromine-d5 Hydrochloride__T715002_【莱耀标准品网】

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(1S,2R)-Tranylcypromine-d5 Hydrochloride

产品基本信息

产品编号：T715002

产品名称：(1S,2R)-Tranylcypromine-d5 Hydrochloride

产品CAS：

规格含量：2.5mg

产品价格：面议

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产品详细介绍

标准品编号:	T715002
名称:	(1S,2R)-Tranylcypromine-d5 Hydrochloride
别名:	Cyclopropanamine, 2-phenyl-, Hydrochloride-d5, (1S,2R)- (9CI); Cyclopropanamine, 2-phenyl-, Hydrochloride-d5, (1S-trans)-;Cyclopropylamine, 2-phenyl-, Hydrochloride-d5, trans-(+)- (8CI); (1S,2R)-2-Phenylcyclopropanamine Hydrochloride-d5; 1-(S)-Amino-2-(R)-phenylcyclopropane Hydrochloride-d5; Tranylcypromine Hydrochloride-d5; d-Tranylcypromine Hydrochloride-d5
参考CAS号:	Unlabeled: 4548-34-9
分子式:	C₉H₆D₅N .HCl
分子量:	138.123646
类别:	Standards; Isotopic Labeled Analogues;
应用:	(1S,2R)-Tranylcypromine Hydrochloride (T715000) is used in the preparation of piperidine derivatives, which serve as LSD1 inhibitors for the treatment of cancer.(1S,2R)-Tranylcypromine Hydrochloride (T715000) has been shown to increase monoamine oxidase inhibition andinhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNVIP(LA)expressing microsomes and Human Liver Microsomes, respectively.
参考文献	Vaisburg, A.; et al.: PCT Int. Appl. 95pp. Patent 2017 CODEN:PIXXD2; Guillem, K.; et al.: J. Neurosci, 25, 8593 (2005); Zhang, W., et al.: Drug Metab. Dispos., 29, 897 (2001); Hong S., et al.: J. Biol. Chem., 255, 9538 (1980); Taavitsainen, P., et al.: Drug Metab. Dispos., 29, 217 (2001); Negishi, T., et al.: Environ. Health Perspect., 112, 1159 (2004)

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