标准品编号:
T007720
名称:
TAS 102 (2:1)
别名:
Tipiracil-trifluridine Mixture (2:1); trifluridine (TFT) and Tipiracil Hydrochloride (TTP) in molar ratio of 1: 0.5; Trifluridine-tipiracil Hydrochloride Mixture;
CAS号:
733030-01-8
参考CAS号:
Component: 183204-72-0 [FreeBase: 183204-74-2] / 7
分子式:
[C₉H₁₁ClN₄O₂ • (HCl)] • 2[ C₁₀H₁₁F₃N₂O₅]
外观:
白色至白色固体
熔点:
170-172°C
分子量:
242.6636463
储存:
Hygroscopic, 冰箱, under inert atmosphere
溶解度:
DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
稳定性:
Hygroscopic
类别:
Standards; Enzyme Activators and Inhibitors; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
TAS 102 (Tipiracil-trifluridine) is a thymidine phosphorylase inhibitor used in chemotherapy treatment of advanced/recurring colorectal cancer.
参考文献
Kimura, M. et al.: Pharmazie., 72, 49 (2017);