Standards; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
D-Phenylalanine-bortezomib is an impurity of Bortezomib (B675700), which is the first proteasome inhibitor drug used to treat cancer in humans. It is related to stereoisomer N-(2-Pyrazinylcarbonyl)-L-phenylalanyl-N-[(1R)-1-borono-3-methylbutyl]-L-phenylalaninamide (P841515) which is a tripeptide boronic acid proteasome inhibitor used as an antitumor agent.