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产品基本信息
产品编号：P165800
产品名称：(S,S)-Palonosetron Hydrochloride
产品CAS：135729-62-3
规格含量：1g
产品价格：面议
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产品详细介绍
标准品编号:
P165800
名称:
(S,S)-Palonosetron Hydrochloride
别名:
(3aS)-2-(3S)-1-Azabicyclo[2.2.2]oct-3-yl-2,3,3a,4,5,6-hexahydro-1H-benz[de]isoquinolin-1-one Hydrochloride; Aloxi; Onicit; RS-25259-197
CAS号:
135729-62-3
参考CAS号:
Free cmpd: 135729-61-2
分子式:
C₁₉H₂₄N₂O • (HCl)
外观:
白色至白色固体
熔点:
238 - 244°C
分子量:
296.413646
储存:
冰箱
溶解度:
Methanol (Slightly, Heated), Water (Slightly)
类别:
Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
(S,S)-Palonosetron Hydrochloride is a serotonin 5-HT3 receptor antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting (CINV). Antiemetic.
参考文献
Clark, R.D., et al.: J. Med. Chem., 36, 2645 (1993), Wong, E.H.F., et al.: Br. J. Pharmacol., 114, 851 (1995), Grunberg, S.M., et al.: Expert. Opin. Pharmacother., 4, 2297 (2003), Eisenberg, P., et al.: Ann. Oncol., 15, 330 (2004), Siddiqui, M.A.A., et al.: Drugs, 64, 1125 (2004),
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