Standards; Chiral Molecules; Pharmaceutical/API Drug Impurities/Metabolites;
应用:
2-O-[4-Oxo-4-(3-pyridinyl)butyl]thymidine, a pyridyloxobutyl DNA adduct, is caused in F344 rats chronically treated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol.