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产品基本信息
产品编号：M312860
产品名称：3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
产品CAS：641571-16-6
规格含量：50mg
产品价格：面议
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产品详细介绍
标准品编号:
M312860
名称:
3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine
CAS号:
641571-16-6
分子式:
C₁₁H₁₀F₃N₃
外观:
白色至Pale Red Solid
熔点:
131-133ºC
分子量:
241.21
储存:
Hygroscopic, 冰箱, under inert atmosphere
溶解度:
DMSO (Slightly), Methanol (Slightly)
稳定性:
Air Sensitive
种类:
Building Blocks; Miscellaneous;
应用:
3-(5-Methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)benzenamine is used in the preparation of c-Src and Abl inhibitors based on the scaffold present in Imatinib (G407000), used in the treatment of myelogenic leukemia.
参考文献
Seeliger, M. et al.: Canc. Res., 69, 2384 (2009); Schindler, T., et al.: Science, 289, 1938 (2000); Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)
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